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法国格勒诺布尔阿尔卑斯大学Xavier Le Guevel教授学术报告

发布单位: 发布时间:2026/04/23

  2026年4月22日,受天津大学姚桥峰教授邀请,格勒诺布尔阿尔卑斯大学CNRS研究主管Xavier Le Guevel教授在天津大学卫津路校区第三教学楼会议室为师生带来一场题为“Development of nanomolecular theranostic agents and instruments for NIR/SWIR detection & therapy”的学术报告。本次报告中, Guevel教授详实地介绍了研究团队在用于近红外、短波红外探测治疗的纳米分子诊疗剂方面的研究进展。



Guevel教授指出,近红外二区/短波红外(NIR-II/SWIR)成像技术与多模态手段、AI及多元图像分析算法深度融合,相较传统NIR-I窗口大幅提升血管探测精度与成像分辨率,在临床应用中已取得显著进展。通过精准调控金纳米团簇基纳米体系的表面化学与组装结构,有效增强SWIR光学发光性能,为多模态诊疗、生物环境下光学性能可控优化提供了优质智能纳米材料。Guevel教授强调,当前研究已理清纳米材料在体内外体系的行为机制,显著提升肿瘤靶向富集与放光疗递送效果。然而如何突破技术瓶颈,真正实现整套诊疗体系的临床落地转化,仍是领域未来最关键的探索方向。


张小涛教授代表团队为Xavier Le Guevel教授赠送纪念品


报告人简介:Dr Xavier Le Guevel obtained his PhD in 2006 in Chemistry from the University of Tours/ French Alternative Energies and Atomic Energy Commission (France). Following this, he did some postdoctoral fellowships in the fields of optical waveguides (Rome, Italy), biosensors (Dublin, Ireland) and pharmaceutical nanotechnology (Saarbruicken, Germany) between 2006 and 2010 before starting as an independent researcher at the Nanomedicine Centre Bionand in Malaga (Spain) in close collaboration with the department of Allergy at Malaga hospital. Since 2016, XLG has been a CNRS researcher, and then CNRS research director since 2023 at the Institute for Advanced Biosciences at the University of Grenoble Alpes (France). XLG was PI on various private and public funded projects (Plan cancer, ARC, ANR, LCC, Merck Serono, Carlos Tercero...) dedicated to the use of nanomaterials for diagnosis and therapy. His work focuses on the development of new nanomaterials such as metal nanoclusters and optical instruments for medical applications and more specifically for cancer treatment and diagnosis from the fundamental research to pre-clinical applications.